• 1How Sequessomes enter into skin?

    After being applied onto skin, water from gel evaporates, and nano-sized sequessomes start squeezing in between skin cells in serach for water-rich environment.

    They move in between skin cells into deeper tissues and eventually reach synovial fluid in joints and line themselves along the cartilages.

    Sequessomes do not enter blod vessels because they are too large to cross into capillaries.

  • 2Sequessomes moving in between skin cells....

  • ... and line along cartilage in joint

    Fluorescent-labeled Sequessomes
    at cartilage surface